Synergistic Activity of Carfilzomib and Panobinostat in Multiple Myeloma Cells via Modulation of ROS Generation and ERK1/2

Relapse of disease and subsequent resistance to established therapies remain as major challenges in the treatment of multiple myeloma (MM). New therapeutic options are needed for these extensively pretreated patients. To explore an optimized combinational therapy, interactions between the irreversib...

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Veröffentlicht in:Biomed Res Int
Hauptverfasser: Gao, Lu, Gao, Minjie, Yang, Guang, Tao, Yi, Kong, Yuanyuan, Yang, Ruixue, Meng, Xiuqin, Ai, Gongwen, Wei, Rong, Wu, Huiqun, Wu, Xiaosong, Shi, Jumei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427084/
https://ncbi.nlm.nih.gov/pubmed/26000292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/459052
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