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Genome-wide pharmacologic unmasking identifies tumor suppressive microRNAs in multiple myeloma

Epigenetic alterations have emerged as an important cause of microRNA (miRNA) deregulation. In Multiple Myeloma (MM), a few tumor suppressive miRNAs silenced by DNA hypermethylation have been reported, but so far there are few systemic investigations on epigenetically silenced miRNAs. We conducted g...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Bi, Chonglei, Chung, Tae-Hoon, Huang, Gaofeng, Zhou, Jianbiao, Yan, Junli, Ahmann, Gregory J., Fonseca, Rafael, Chng, Wee Joo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694918/
https://ncbi.nlm.nih.gov/pubmed/26164366
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