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A Novel Measure of Chromosome Instability Can Account for Prognostic Difference in Multiple Myeloma

Multiple myeloma (MM) is characterized by complex genetic abnormalities whose complexity signifies varying degree of chromosomal instability (CIN). In this study, we introduced a novel CIN measure, chromosome instability genome event count (CINGEC), which considered both copy number aberrations and...

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Detalhes bibliográficos
Main Authors: Chung, Tae-Hoon, Mulligan, George, Fonseca, Rafael, Chng, Wee Joo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688789/
https://ncbi.nlm.nih.gov/pubmed/23840451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066361
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