IKK inhibition increases bortezomib effectiveness in ovarian cancer

Ovarian cancer is associated with increased expression of the pro-angiogenic chemokine interleukin-8 (IL-8, CXCL8), which induces tumor cell proliferation, angiogenesis, and metastasis. Even though bortezomib (BZ) has shown remarkable anti-tumor activity in hematological malignancies, it has been le...

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Pubblicato in:Oncotarget
Autori principali: Singha, Bipradeb, Gatla, Himavanth Reddy, Phyo, Sai, Patel, Atish, Chen, Zhe-Sheng, Vancurova, Ivana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694906/
https://ncbi.nlm.nih.gov/pubmed/26267322
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