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TNF signaling mediates an enzalutamide-induced metastatic phenotype of prostate cancer and microenvironment cell co-cultures

The dramatic responses tumors display to targeted therapies are limited by acquired or pre-existing mechanisms of therapy resistance. We recently discovered that androgen receptor blockade by the anti-androgen enzalutamide paradoxically enhanced metastasis and that these pro-metastatic effects were...

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Publicat a:Oncotarget
Autors principals: Sha, Kai, Yeh, Shuyuan, Chang, Chawnshang, Nastiuk, Kent L., Krolewski, John J.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694862/
https://ncbi.nlm.nih.gov/pubmed/26327448
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