Modeling-Enabled Characterization of Novel NLRX1 Ligands

Nucleotide-binding domain and leucine-rich repeat containing (NLR) family are intracellular sentinels of cytosolic homeostasis that orchestrate immune and inflammatory responses in infectious and immune-mediated diseases. NLRX1 is a mitochondrial-associated NOD-like receptor involved in the modulati...

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Veröffentlicht in:PLoS One
Hauptverfasser: Lu, Pinyi, Hontecillas, Raquel, Abedi, Vida, Kale, Shiv, Leber, Andrew, Heltzel, Chase, Langowski, Mark, Godfrey, Victoria, Philipson, Casandra, Tubau-Juni, Nuria, Carbo, Adria, Girardin, Stephen, Uren, Aykut, Bassaganya-Riera, Josep
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694766/
https://ncbi.nlm.nih.gov/pubmed/26714018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145420
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