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Argininamide Binding Arrests Global Motions in HIV-1 TAR RNA: Comparison with Mg(2+)-induced Conformational Stabilization

The structure and dynamics of the stem-loop transactivation response element (TAR) RNA from the human immunodeficiency virus type-1 (HIV-1) bound to the ligand argininamide (ARG) has been characterized using a combination of a large number of residual dipolar couplings (RDCs) and trans-hydrogen bond...

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發表在:J Mol Biol
Main Authors: Pitt, Stephen W., Majumdar, Ananya, Serganov, Alexander, Patel, Dinshaw J., Al-Hashimi, Hashim M.
格式: Artigo
語言:Inglês
出版: 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694592/
https://ncbi.nlm.nih.gov/pubmed/15050819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2004.02.031
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