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Structural and Dynamic Basis for Low Affinity-High Selectivity Binding of L-glutamine by the Glutamine Riboswitch

Naturally occurring L-glutamine riboswitches occur in cyanobacteria and marine metagenomes where they reside upstream of genes involved in nitrogen metabolism. By combining X-ray, NMR and MD, we characterized a L-glutamine-dependent conformational transition in the Synechococcus elongatus glutamine...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Ren, Aiming, Xue, Yi, Peselis, Alla, Serganov, Alexander, Al-Hashimi, Hashim M., Patel, Dinshaw J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690532/
https://ncbi.nlm.nih.gov/pubmed/26655897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.062
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