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Analysis of genetic variations in CYP2C9, CYP2C19, CYP2D6 and CYP3A5 genes using oligonucleotide microarray

The cytochrome P450 enzymes play a critical role in the metabolism of many commonly prescribed drugs. Among them, the most important enzymes are highly polymorphic CYP2C9, CYP2C19, CYP2D6 and CYP3A5, which are responsible for about 40% of the metabolism of clinical used drugs. Here we developed a no...

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Detalles Bibliográficos
Publicado en:Int J Clin Exp Med
Main Authors: Dong, Yuanyuan, Xiao, Huasheng, Wang, Qi, Zhang, Chunxiu, Liu, Xiuming, Yao, Na, Sheng, Haihui, Li, Haiyan
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694416/
https://ncbi.nlm.nih.gov/pubmed/26770516
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