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Investigation of PI3K/PKB/mTOR/S6K1 signaling pathway in relationship of type 2 diabetes and Alzheimer’s disease

The aim of this study was to investigate the roles of PI3K/PKB/mTOR/S6K1 signaling pathway in the risk-increasing mechanisms of type 2 diabetes mellitus (T2DM) towards the Alzheimer’s disease (AD). Based on the high-sugar high-fat diet, the single intraperitoneal injection of streptozotocin was perf...

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Dettagli Bibliografici
Pubblicato in:Int J Clin Exp Med
Autori principali: Ma, Yunqing, Wu, Dongke, Zhang, Wei, Liu, Jiankun, Chen, Siping, Hua, Binghong
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694371/
https://ncbi.nlm.nih.gov/pubmed/26770471
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