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Insights into the PI3-K-PKB-mTOR signalling pathway from small molecules
This review describes the progress that has been made in understanding the PI3-K-PKB-mTOR signalling pathway by using small molecules as pharmacological probes. It briefly covers the structural characteristics, regulation of and downstream effects of several key regulators of PI3-K-PKB-mTOR signalli...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer-Verlag
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2698322/ https://ncbi.nlm.nih.gov/pubmed/19568798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12154-008-0008-0 |
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