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Insights into the PI3-K-PKB-mTOR signalling pathway from small molecules

This review describes the progress that has been made in understanding the PI3-K-PKB-mTOR signalling pathway by using small molecules as pharmacological probes. It briefly covers the structural characteristics, regulation of and downstream effects of several key regulators of PI3-K-PKB-mTOR signalli...

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Detalhes bibliográficos
Main Authors: Gunn, Richard M., Hailes, Helen C.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698322/
https://ncbi.nlm.nih.gov/pubmed/19568798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12154-008-0008-0
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