Characterization of Mycobacterium smegmatis sigF mutant and its regulon: overexpression of SigF antagonist (MSMEG_1803) in M. smegmatis mimics sigF mutant phenotype, loss of pigmentation, and sensitivity to oxidative stress

In Mycobacterium smegmatis, sigF is widely expressed during different growth stages and plays role in adaptation to stationary phase and oxidative stress. Using a sigF deletion mutant of M. smegmatis mc(2)155, we demonstrate that SigF is not essential for growth of bacterium. Deletion of sigF result...

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Detalhes bibliográficos
Publicado no:Microbiologyopen
Main Authors: Singh, Anirudh K., Dutta, Debashis, Singh, Vandana, Srivastava, Vishal, Biswas, Rajesh K., Singh, Bhupendra N.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694148/
https://ncbi.nlm.nih.gov/pubmed/26434659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.288
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