Accumulation of Regulatory T Cells and Chronic Inflammation in the Middle Ear in a Mouse Model of Chronic Otitis Media with Effusion Induced by Combined Eustachian Tube Blockage and Nontypeable Haemophilus influenzae Infection

Nontypeable Haemophilus influenzae (NTHi) is associated with chronic otitis media (COM). In this study, we generated a murine model of COM by using eustachian tube (ET) obstruction and NTHi (10(7) CFU) inoculation into the tympanic bulla, and we investigated the relationship between regulatory T cel...

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Vydáno v:Infect Immun
Hlavní autoři: Hirano, Takashi, Kodama, Satoru, Kawano, Toshiaki, Suzuki, Masashi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Bacterial Infections
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694021/
https://ncbi.nlm.nih.gov/pubmed/26553466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01128-15
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