Accumulation of Regulatory T Cells and Chronic Inflammation in the Middle Ear in a Mouse Model of Chronic Otitis Media with Effusion Induced by Combined Eustachian Tube Blockage and Nontypeable Haemophilus influenzae Infection

Nontypeable Haemophilus influenzae (NTHi) is associated with chronic otitis media (COM). In this study, we generated a murine model of COM by using eustachian tube (ET) obstruction and NTHi (10(7) CFU) inoculation into the tympanic bulla, and we investigated the relationship between regulatory T cel...

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Bibliografische gegevens
Gepubliceerd in:Infect Immun
Hoofdauteurs: Hirano, Takashi, Kodama, Satoru, Kawano, Toshiaki, Suzuki, Masashi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2015
Onderwerpen:
Bacterial Infections
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694021/
https://ncbi.nlm.nih.gov/pubmed/26553466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01128-15
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