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Brucella abortus Invasion of Osteocytes Modulates Connexin 43 and Integrin Expression and Induces Osteoclastogenesis via Receptor Activator of NF-κB Ligand and Tumor Necrosis Factor Alpha Secretion

Osteoarticular brucellosis is the most common localization of human active disease. Osteocytes are the most abundant cells of bone. They secrete factors that regulate the differentiation of both osteoblasts and osteoclasts during bone remodeling. The aim of this study is to determine if Brucella abo...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Pesce Viglietti, Ayelén Ivana, Arriola Benitez, Paula Constanza, Gentilini, María Virginia, Velásquez, Lis Noelia, Fossati, Carlos Alberto, Giambartolomei, Guillermo Hernán, Delpino, María Victoria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694014/
https://ncbi.nlm.nih.gov/pubmed/26459511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01049-15
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