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Inhibition of interleukin‐1β‐mediated interleukin‐1 receptor‐associated kinase 4 phosphorylation by zinc leads to repression of memory T helper type 17 response in humans

Zinc is an essential trace element that plays pivotal roles in multiple facets of the immune system. Besides its catalytic and structural roles, zinc also functions as an intracellular signalling molecule, and changes in zinc levels can cause both direct and indirect modulation of immune responses....

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Lee, Hyunju, Kim, Bonah, Choi, Yeon Ho, Hwang, Yuri, Kim, Dong Hyun, Cho, Sunjung, Hong, Sung Jun, Lee, Won‐Woo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693897/
https://ncbi.nlm.nih.gov/pubmed/26407164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12536
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