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The law of mass action and the pharmacological concentration–effect curve: resolving the paradox of apparently non‐dose‐related adverse drug reactions

BACKGROUND: Adverse drug reactions are sometimes described as being ‘non‐dose‐related’ because no relationship has been found between increasing doses and either the intensity of the response or the proportion of individuals in whom the response occurs; furthermore, hypersensitivity reactions are of...

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Detaylı Bibliyografya
Yayımlandı:Br J Clin Pharmacol
Asıl Yazarlar: Aronson, Jeffrey K., Ferner, Robin E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693576/
https://ncbi.nlm.nih.gov/pubmed/26119837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12706
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