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Ubiquitin‐Activated Interaction Traps (UBAITs) identify E3 ligase binding partners
We describe a new class of reagents for identifying substrates, adaptors, and regulators of HECT and RING E3s. UBAITs (Ubiquitin‐Activated Interaction Traps) are E3‐ubiquitin fusion proteins and, in an E1‐ and E2‐dependent manner, the C‐terminal ubiquitin moiety forms an amide linkage to proteins th...
Tallennettuna:
| Julkaisussa: | EMBO Rep |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
John Wiley and Sons Inc.
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4693525/ https://ncbi.nlm.nih.gov/pubmed/26508657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540620 |
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