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The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging
Sarcopenia, the loss of skeletal muscle mass and function during aging, is a major contributor to disability and frailty in the elderly. Previous studies found a protective effect of reduced histone deacetylase activity in models of neurogenic muscle atrophy. Because loss of muscle mass during aging...
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| 發表在: | Aging Cell |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4693467/ https://ncbi.nlm.nih.gov/pubmed/26290460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12387 |
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