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The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging

Sarcopenia, the loss of skeletal muscle mass and function during aging, is a major contributor to disability and frailty in the elderly. Previous studies found a protective effect of reduced histone deacetylase activity in models of neurogenic muscle atrophy. Because loss of muscle mass during aging...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Aging Cell
Egile Nagusiak: Walsh, Michael E., Bhattacharya, Arunabh, Sataranatarajan, Kavithalakshmi, Qaisar, Rizwan, Sloane, Lauren, Rahman, Md M., Kinter, Michael, Van Remmen, Holly
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693467/
https://ncbi.nlm.nih.gov/pubmed/26290460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12387
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