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Apoptosis and necrosis mediate skeletal muscle fiber loss in age‐induced mitochondrial enzymatic abnormalities

Sarcopenia, the age‐induced loss of skeletal muscle mass and function, results from the contributions of both fiber atrophy and loss of myofibers. We have previously characterized sarcopenia in FBN rats, documenting age‐dependent declines in muscle mass and fiber number along with increased fiber at...

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Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Cheema, Nashwa, Herbst, Allen, McKenzie, Debbie, Aiken, Judd M.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693455/
https://ncbi.nlm.nih.gov/pubmed/26365892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12399
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