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Apoptosis and necrosis mediate skeletal muscle fiber loss in age‐induced mitochondrial enzymatic abnormalities

Sarcopenia, the age‐induced loss of skeletal muscle mass and function, results from the contributions of both fiber atrophy and loss of myofibers. We have previously characterized sarcopenia in FBN rats, documenting age‐dependent declines in muscle mass and fiber number along with increased fiber at...

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Bibliographische Detailangaben
Veröffentlicht in:Aging Cell
Hauptverfasser: Cheema, Nashwa, Herbst, Allen, McKenzie, Debbie, Aiken, Judd M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693455/
https://ncbi.nlm.nih.gov/pubmed/26365892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12399
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