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Apoptosis and necrosis mediate skeletal muscle fiber loss in age‐induced mitochondrial enzymatic abnormalities

Sarcopenia, the age‐induced loss of skeletal muscle mass and function, results from the contributions of both fiber atrophy and loss of myofibers. We have previously characterized sarcopenia in FBN rats, documenting age‐dependent declines in muscle mass and fiber number along with increased fiber at...

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Publicat a:Aging Cell
Autors principals: Cheema, Nashwa, Herbst, Allen, McKenzie, Debbie, Aiken, Judd M.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693455/
https://ncbi.nlm.nih.gov/pubmed/26365892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12399
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