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Apoptosis and necrosis mediate skeletal muscle fiber loss in age‐induced mitochondrial enzymatic abnormalities

Sarcopenia, the age‐induced loss of skeletal muscle mass and function, results from the contributions of both fiber atrophy and loss of myofibers. We have previously characterized sarcopenia in FBN rats, documenting age‐dependent declines in muscle mass and fiber number along with increased fiber at...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Cheema, Nashwa, Herbst, Allen, McKenzie, Debbie, Aiken, Judd M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693455/
https://ncbi.nlm.nih.gov/pubmed/26365892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12399
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