Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure

Endothelial dysfunction is a critical factor in many cardiovascular diseases, including hypertension. Although lipid signaling has been implicated in endothelial dysfunction and cardiovascular disease, specific molecular mechanisms are poorly understood. Here we report that Nogo-B, a membrane protei...

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Gepubliceerd in:Nat Med
Hoofdauteurs: Cantalupo, Anna, Zhang, Yi, Kothiya, Milankumar, Galvani, Sylvain, Obinata, Hideru, Bucci, Mariarosaria, Giordano, Frank J, Jiang, Xian-Cheng, Hla, Timothy, Di Lorenzo, Annarita
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692717/
https://ncbi.nlm.nih.gov/pubmed/26301690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3934
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