Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure

Endothelial dysfunction is a critical factor in many cardiovascular diseases, including hypertension. Although lipid signaling has been implicated in endothelial dysfunction and cardiovascular disease, specific molecular mechanisms are poorly understood. Here we report that Nogo-B, a membrane protei...

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Bibliographic Details
Published in:Nat Med
Main Authors: Cantalupo, Anna, Zhang, Yi, Kothiya, Milankumar, Galvani, Sylvain, Obinata, Hideru, Bucci, Mariarosaria, Giordano, Frank J, Jiang, Xian-Cheng, Hla, Timothy, Di Lorenzo, Annarita
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692717/
https://ncbi.nlm.nih.gov/pubmed/26301690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3934
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