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Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure

Endothelial dysfunction is a critical factor in many cardiovascular diseases, including hypertension. Although lipid signaling has been implicated in endothelial dysfunction and cardiovascular disease, specific molecular mechanisms are poorly understood. Here we report that Nogo-B, a membrane protei...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Med
Hauptverfasser: Cantalupo, Anna, Zhang, Yi, Kothiya, Milankumar, Galvani, Sylvain, Obinata, Hideru, Bucci, Mariarosaria, Giordano, Frank J, Jiang, Xian-Cheng, Hla, Timothy, Di Lorenzo, Annarita
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692717/
https://ncbi.nlm.nih.gov/pubmed/26301690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3934
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