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Dissecting Proton Delocalization in an Enzyme’s Hydrogen Bond Network with Unnatural Amino Acids
Extended hydrogen bond networks are a common structural motif of enzymes. A recent analysis proposed quantum delocalization of protons as a feature present in the hydrogen bond network spanning a triad of tyrosines (Y(16), Y(32), and Y(57)) in the active site of ketosteroid isomerase (KSI), contribu...
Shranjeno v:
| izdano v: | Biochemistry |
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| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4692369/ https://ncbi.nlm.nih.gov/pubmed/26571340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00958 |
| Oznake: |
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