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Hsp90·Cdc37 Complexes with Protein Kinases Form Cooperatively with Multiple Distinct Interaction Sites

Protein kinases are the most prominent group of heat shock protein 90 (Hsp90) clients and are recruited to the molecular chaperone by the kinase-specific cochaperone cell division cycle 37 (Cdc37). The interaction between Hsp90 and nematode Cdc37 is mediated by binding of the Hsp90 middle domain to...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Eckl, Julia M., Scherr, Matthias J., Freiburger, Lee, Daake, Marina A., Sattler, Michael, Richter, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692213/
https://ncbi.nlm.nih.gov/pubmed/26511315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.693150
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