Pharmacodynamic monitoring of (immuno)proteasome inhibition during bortezomib treatment of a critically ill patient with lupus nephritis and myocarditis

OBJECTIVE: To describe the pharmacodynamic monitoring of (immuno)proteasome inhibition following treatment with bortezomib in a therapy-refractory systemic lupus erythematosus (SLE) patient with life-threatening myocarditis and lupus nephritis. PATIENT AND METHODS: Inhibition of catalytic activities...

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Detalhes bibliográficos
Publicado no:Lupus Sci Med
Main Authors: de Groot, Karina A, Tsang a Sjoe, Michel, Niewerth, Denise, Cloos, Jacqueline, Blank, Jonathan L, Niessen, Hans W M, Zweegman, Sonja, Voskuyl, Alexandre E, Jansen, Gerrit, van der Heijden, Joost W
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2015
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691954/
https://ncbi.nlm.nih.gov/pubmed/26719810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/lupus-2015-000121
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