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Dynamic changes in histone modifications precede de novo DNA methylation in oocytes

Erasure and subsequent reinstatement of DNA methylation in the germline, especially at imprinted CpG islands (CGIs), is crucial to embryogenesis in mammals. The mechanisms underlying DNA methylation establishment remain poorly understood, but a number of post-translational modifications of histones...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Stewart, Kathleen R., Veselovska, Lenka, Kim, Jeesun, Huang, Jiahao, Saadeh, Heba, Tomizawa, Shin-ichi, Smallwood, Sébastien A., Chen, Taiping, Kelsey, Gavin
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691949/
https://ncbi.nlm.nih.gov/pubmed/26584620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.271353.115
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