Dynamic changes in histone modifications precede de novo DNA methylation in oocytes

Erasure and subsequent reinstatement of DNA methylation in the germline, especially at imprinted CpG islands (CGIs), is crucial to embryogenesis in mammals. The mechanisms underlying DNA methylation establishment remain poorly understood, but a number of post-translational modifications of histones...

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Bibliografische gegevens
Gepubliceerd in:Genes Dev
Hoofdauteurs: Stewart, Kathleen R., Veselovska, Lenka, Kim, Jeesun, Huang, Jiahao, Saadeh, Heba, Tomizawa, Shin-ichi, Smallwood, Sébastien A., Chen, Taiping, Kelsey, Gavin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2015
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691949/
https://ncbi.nlm.nih.gov/pubmed/26584620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.271353.115
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