Deep sequencing and de novo assembly of the mouse oocyte transcriptome define the contribution of transcription to the DNA methylation landscape

BACKGROUND: Previously, a role was demonstrated for transcription in the acquisition of DNA methylation at imprinted control regions in oocytes. Definition of the oocyte DNA methylome by whole genome approaches revealed that the majority of methylated CpG islands are intragenic and gene bodies are h...

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Dettagli Bibliografici
Pubblicato in:Genome Biol
Autori principali: Veselovska, Lenka, Smallwood, Sebastien A., Saadeh, Heba, Stewart, Kathleen R., Krueger, Felix, Maupetit-Méhouas, Stéphanie, Arnaud, Philippe, Tomizawa, Shin-ichi, Andrews, Simon, Kelsey, Gavin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582738/
https://ncbi.nlm.nih.gov/pubmed/26408185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0769-z
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