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C-terminal threonine reduces Aβ(43) amyloidogenicity compared with Aβ(42)
Aβ(43), a product of the proteolysis of the amyloid precursor protein APP, is related to Aβ(42) by an additional Thr residue at the C-terminus. Aβ(43) is typically generated at low levels compared with the predominant Aβ(42) and Aβ(40) forms, but it has been suggested that this longer peptide might...
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| Vydáno v: | J Mol Biol |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4691432/ https://ncbi.nlm.nih.gov/pubmed/26122432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.06.008 |
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