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An Efficient Labelling Approach to Harness Backbone and Side-Chain Protons in (1)H-Detected Solid-State NMR Spectroscopy

(1)H-detection can greatly improve spectral sensitivity in biological solid-state NMR (ssNMR), thus allowing the study of larger and more complex proteins. However, the general requirement to perdeuterate proteins critically curtails the potential of (1)H-detection by the loss of aliphatic side-chai...

詳細記述

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書誌詳細
出版年:Angew Chem Int Ed Engl
主要な著者: Mance, Deni, Sinnige, Tessa, Kaplan, Mohammed, Narasimhan, Siddarth, Daniëls, Mark, Houben, Klaartje, Baldus, Marc, Weingarth, Markus
フォーマット: Artigo
言語:Inglês
出版事項: WILEY-VCH Verlag 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691318/
https://ncbi.nlm.nih.gov/pubmed/26555653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201509170
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