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Combination Treatment with Sublethal Ionizing Radiation and the Proteasome Inhibitor, Bortezomib, Enhances Death-Receptor Mediated Apoptosis and Anti-Tumor Immune Attack

Sub-lethal doses of radiation can modulate gene expression, making tumor cells more susceptible to T-cell-mediated immune attack. Proteasome inhibitors demonstrate broad anti-tumor activity in clinical and pre-clinical cancer models. Here, we use a combination treatment of proteasome inhibition and...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Cacan, Ercan, Spring, Alexander M., Kumari, Anita, Greer, Susanna F., Garnett-Benson, Charlie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691179/
https://ncbi.nlm.nih.gov/pubmed/26703577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161226238
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