Turning T cells on: epigenetically enhanced expression of effector T-cell costimulatory molecules on irradiated human tumor cells

BACKGROUND: Sub-lethal doses of radiation can alter the phenotype of target tissue by modulating gene expression and making tumor cells more susceptible to T-cell-mediated immune attack. We have previously shown that sub-lethal tumor cell irradiation enhances killing of colorectal carcinoma cells by...

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Bibliografiska uppgifter
Huvudupphovsmän: Kumari, Anita, Cacan, Ercan, Greer, Susanna F, Garnett-Benson, Charlie
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019910/
https://ncbi.nlm.nih.gov/pubmed/24829753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-1426-1-17
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