Alterations of Dopamine D2 Receptors and Related Receptor-Interacting Proteins in Schizophrenia: The Pivotal Position of Dopamine Supersensitivity Psychosis in Treatment-Resistant Schizophrenia

Although the dopamine D2 receptor (DRD2) has been a main target of antipsychotic pharmacotherapy for the treatment of schizophrenia, the standard treatment does not offer sufficient relief of symptoms to 20%–30% of patients suffering from this disorder. Moreover, over 80% of patients experience rela...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Oda, Yasunori, Kanahara, Nobuhisa, Iyo, Masaomi
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2015
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691170/
https://ncbi.nlm.nih.gov/pubmed/26694375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161226228
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