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Genetic association between G protein-coupled receptor kinase 6/β-arrestin 2 and dopamine supersensitivity psychosis in schizophrenia

BACKGROUND/AIM: Dopamine supersensitivity psychosis (DSP), clinically characterized by unstable and severe psychosis or tardive dyskinesia and often categorized as treatment-resistant schizophrenia, is promoted by long-term antipsychotic treatment. An upregulation of the dopamine D(2) receptor cause...

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Detalhes bibliográficos
Publicado no:Neuropsychiatr Dis Treat
Main Authors: Oda, Yasunori, Kanahara, Nobuhisa, Kimura, Hiroshi, Watanabe, Hiroyuki, Hashimoto, Kenji, Iyo, Masaomi
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524575/
https://ncbi.nlm.nih.gov/pubmed/26251601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S86042
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