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DNA Double Strand Break Response and Limited Repair Capacity in Mouse Elongated Spermatids
Spermatids are extremely sensitive to genotoxic exposures since during spermiogenesis only error-prone non homologous end joining (NHEJ) repair pathways are available. Hence, genomic damage may accumulate in sperm and be transmitted to the zygote. Indirect, delayed DNA fragmentation and lesions asso...
Guardat en:
| Publicat a: | Int J Mol Sci |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4691157/ https://ncbi.nlm.nih.gov/pubmed/26694360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161226214 |
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