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DNA Double Strand Break Response and Limited Repair Capacity in Mouse Elongated Spermatids
Spermatids are extremely sensitive to genotoxic exposures since during spermiogenesis only error-prone non homologous end joining (NHEJ) repair pathways are available. Hence, genomic damage may accumulate in sperm and be transmitted to the zygote. Indirect, delayed DNA fragmentation and lesions asso...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4691157/ https://ncbi.nlm.nih.gov/pubmed/26694360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161226214 |
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