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Molecular Evolution of the TET Gene Family in Mammals

Ten-eleven translocation (TET) proteins, a family of Fe(2+)- and 2-oxoglutarate-dependent dioxygenases, are involved in DNA demethylation. They also help regulate various cellular functions. Three TET paralogs have been identified (TET1, TET2, and TET3) in humans. This study focuses on the evolution...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Akahori, Hiromichi, Guindon, Stéphane, Yoshizaki, Sumio, Muto, Yoshinori
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691057/
https://ncbi.nlm.nih.gov/pubmed/26633372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161226110
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