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Molecular Evolution of the TET Gene Family in Mammals

Ten-eleven translocation (TET) proteins, a family of Fe(2+)- and 2-oxoglutarate-dependent dioxygenases, are involved in DNA demethylation. They also help regulate various cellular functions. Three TET paralogs have been identified (TET1, TET2, and TET3) in humans. This study focuses on the evolution...

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Pubblicato in:Int J Mol Sci
Autori principali: Akahori, Hiromichi, Guindon, Stéphane, Yoshizaki, Sumio, Muto, Yoshinori
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691057/
https://ncbi.nlm.nih.gov/pubmed/26633372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161226110
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