Glucose-6-Phosphate Dehydrogenase Enhances Antiviral Response through Downregulation of NADPH Sensor HSCARG and Upregulation of NF-κB Signaling

Glucose-6-phosphate dehydrogenase (G6PD)-deficient cells are highly susceptible to viral infection. This study examined the mechanism underlying this phenomenon by measuring the expression of antiviral genes—tumor necrosis factor alpha (TNF-α) and GTPase myxovirus resistance 1 (MX1)—in G6PD-knockdow...

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Detalles Bibliográficos
Publicado en:Viruses
Main Authors: Wu, Yi-Hsuan, Chiu, Daniel Tsun-Yee, Lin, Hsin-Ru, Tang, Hsiang-Yu, Cheng, Mei-Ling, Ho, Hung-Yao
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690889/
https://ncbi.nlm.nih.gov/pubmed/26694452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7122966
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