Glucose-6-phosphate dehydrogenase is indispensable in embryonic development by modulation of epithelial-mesenchymal transition via the NOX/Smad3/miR-200b axis

Glucose-6-phosphate dehydrogenase (G6PD) is a housekeeping enzyme involved in the pentose phosphate shunt for producing nicotinamide adenine dinucleotide phosphate (NADPH). Severe G6PD deficiency leads to embryonic lethality, but the underlying mechanism is unclear. In the current study, the effects...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wu, Yi-Hsuan, Lee, Ying-Hsuan, Shih, Hung-Yu, Chen, Shih-Hsiang, Cheng, Yi-Chuan, Tsun-Yee Chiu, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849038/
https://ncbi.nlm.nih.gov/pubmed/29317613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0005-8
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