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Potential Broad Spectrum Inhibitors of the Coronavirus 3CL(pro): A Virtual Screening and Structure-Based Drug Design Study

Human coronaviruses represent a significant disease burden; however, there is currently no antiviral strategy to combat infection. The outbreak of severe acute respiratory syndrome (SARS) in 2003 and Middle East respiratory syndrome (MERS) less than 10 years later demonstrates the potential of coron...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Berry, Michael, Fielding, Burtram C., Gamieldien, Junaid
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690886/
https://ncbi.nlm.nih.gov/pubmed/26694449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7122963
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