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The evaluation of the therapeutic efficacy and side effects of a macromolecular dexamethasone prodrug in the collagen-induced arthritis mouse model

PURPOSE: To investigate the efficacy and safety of N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-dexamethasone conjugate (P-Dex) in the collagen-induced arthritis (CIA) mouse model. METHODS: HPMA copolymer labeled with a near infrared fluorescence (NIRF) dye was administered to mice with CIA to...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pharm Res
Egile Nagusiak: Quan, Lingdong, Zhang, Yijia, Dusad, Anand, Ren, Ke, Purdue, P. Edward, Goldring, Steven R., Wang, Dong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690754/
https://ncbi.nlm.nih.gov/pubmed/26286188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-015-1776-1
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