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Efficient Synthesis of β-CF(3)/SCF(3) Substituted Carbonyls via Copper-Catalyzed Electrophilic Ring-Opening Cross-Coupling of Cyclopropanols

The first copper-catalyzed ring-opening electrophilic trifluoromethylation and trifluoromethylthiolation of cyclopropanols to form C(sp3)-CF(3) and C(sp3)-SCF(3) bonds have been realized. These transformations are efficient for the synthesis of β-CF(3) and β-SCF(3) substituted carbonyl compounds tha...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Li, Yong, Ye, Zhishi, Bellman, Tabitha M., Chi, Teng, Dai, Mingji
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690544/
https://ncbi.nlm.nih.gov/pubmed/25885795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.5b00782
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