Potential anti-cancer effect of N-hydroxy-7-(2-naphthylthio) heptanomide (HNHA), a novel histone deacetylase inhibitor, for the treatment of thyroid cancer

BACKGROUND: Thyroid cancer has been indicated to have a higher global proportion of DNA methylation and a decreased level of histone acetylation. Previous studies showed that histone gene reviser and epigenetic changes role significant parts in papillary and anaplastic thyroid cancer tumorigenesis....

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Pubblicato in:BMC Cancer
Autori principali: Kim, Seok-Mo, Park, Ki-Cheong, Jeon, Jeong-Yong, Kim, Bup-Woo, Kim, Hyeung-Kyoo, Chang, Ho-Jin, Choi, Seung-Hoon, Park, Cheong-Soo, Chang, Hang-Seok
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690331/
https://ncbi.nlm.nih.gov/pubmed/26698299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1982-6
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