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A forest-based feature screening approach for large-scale genome data with complex structures

BACKGROUND: Genome-wide association studies (GWAS) interrogate large-scale whole genome to characterize the complex genetic architecture for biomedical traits. When the number of SNPs dramatically increases to half million but the sample size is still limited to thousands, the traditional p-value ba...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Genet
Hauptverfasser: Wang, Gang, Fu, Guifang, Corcoran, Christopher
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690313/
https://ncbi.nlm.nih.gov/pubmed/26698561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-015-0294-9
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