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A forest-based feature screening approach for large-scale genome data with complex structures

BACKGROUND: Genome-wide association studies (GWAS) interrogate large-scale whole genome to characterize the complex genetic architecture for biomedical traits. When the number of SNPs dramatically increases to half million but the sample size is still limited to thousands, the traditional p-value ba...

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Detalhes bibliográficos
Publicado no:BMC Genet
Main Authors: Wang, Gang, Fu, Guifang, Corcoran, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690313/
https://ncbi.nlm.nih.gov/pubmed/26698561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-015-0294-9
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