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A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions

BACKGROUND: Genetic interactions, or non-additive effects between genes, play a crucial role in many cellular processes and disease. Which mechanisms underlie these genetic interactions has hardly been characterized. Understanding the molecular basis of genetic interactions is crucial in deciphering...

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發表在:BMC Biol
Main Authors: Sameith, Katrin, Amini, Saman, Groot Koerkamp, Marian J. A., van Leenen, Dik, Brok, Mariel, Brabers, Nathalie, Lijnzaad, Philip, van Hooff, Sander R., Benschop, Joris J., Lenstra, Tineke L., Apweiler, Eva, van Wageningen, Sake, Snel, Berend, Holstege, Frank C. P., Kemmeren, Patrick
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690272/
https://ncbi.nlm.nih.gov/pubmed/26700642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0222-5
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