A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions

BACKGROUND: Genetic interactions, or non-additive effects between genes, play a crucial role in many cellular processes and disease. Which mechanisms underlie these genetic interactions has hardly been characterized. Understanding the molecular basis of genetic interactions is crucial in deciphering...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Biol
Main Authors: Sameith, Katrin, Amini, Saman, Groot Koerkamp, Marian J. A., van Leenen, Dik, Brok, Mariel, Brabers, Nathalie, Lijnzaad, Philip, van Hooff, Sander R., Benschop, Joris J., Lenstra, Tineke L., Apweiler, Eva, van Wageningen, Sake, Snel, Berend, Holstege, Frank C. P., Kemmeren, Patrick
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690272/
https://ncbi.nlm.nih.gov/pubmed/26700642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0222-5
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