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MixChIP: a probabilistic method for cell type specific protein-DNA binding analysis

BACKGROUND: Transcription factors (TFs) are proteins that bind to DNA and regulate gene expression. To understand details of gene regulation, characterizing TF binding sites in different cell types, diseases and among individuals is essential. However, sometimes TF binding can only be measured from...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Rautio, Sini, Lähdesmäki, Harri
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690251/
https://ncbi.nlm.nih.gov/pubmed/26703974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0834-3
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