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TIP: A probabilistic method for identifying transcription factor target genes from ChIP-seq binding profiles

Motivation: ChIP-seq and ChIP-chip experiments have been widely used to identify transcription factor (TF) binding sites and target genes. Conventionally, a fairly ‘simple’ approach is employed for target gene identification e.g. finding genes with binding sites within 2 kb of a transcription start...

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Detalhes bibliográficos
Main Authors: Cheng, Chao, Min, Renqiang, Gerstein, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223362/
https://ncbi.nlm.nih.gov/pubmed/22039215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr552
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