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Specific degradation of phosphatidylglycerol is necessary for proper mitochondrial morphology and function
In yeast, phosphatidylglycerol (PG) is a minor phospholipid under standard conditions; it can be utilized for cardiolipin (CL) biosynthesis by CL synthase, Crd1p, or alternatively degraded by the phospholipase Pgc1p. The Saccharomyces cerevisiae deletion mutants crd1Δ and pgc1Δ both accumulate PG. B...
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| Veröffentlicht in: | Biochim Biophys Acta |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4690203/ https://ncbi.nlm.nih.gov/pubmed/26482708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2015.10.004 |
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