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Specific degradation of phosphatidylglycerol is necessary for proper mitochondrial morphology and function

In yeast, phosphatidylglycerol (PG) is a minor phospholipid under standard conditions; it can be utilized for cardiolipin (CL) biosynthesis by CL synthase, Crd1p, or alternatively degraded by the phospholipase Pgc1p. The Saccharomyces cerevisiae deletion mutants crd1Δ and pgc1Δ both accumulate PG. B...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Pokorná, Lucia, Čermáková, Petra, Horváth, Anton, Baile, Matthew G., Claypool, Steven M., Griač, Peter, Malínský, Jan, Balážová, Mária
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690203/
https://ncbi.nlm.nih.gov/pubmed/26482708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2015.10.004
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